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Frances Farmer -- Frances Farmer died at the age of 57, destitute and a shell of the once-promising movie star. While in mental hospitals she was raped, subjected to electro-shock and insulin shock therapy, heavily medicated and, many believe, finally subjected to a lobotomy.
Vivien Leigh 1913-1967: The Avoidable Tragedy -- Diagnosed as manic depressive, she suffered a long-term underlying physical condition, tuberculosis, which can manifest as a so-called ''psychiatric disorder.'' A drug used to treat TB also has the side effects of mental confusion and toxic psychosis.

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